Start Date
November 30, 2021
Primary Completion Date
May 31, 2022
Study Completion Date
May 31, 2022
Squat-to-stand maneuver
Subjects will squat for 5 seconds and then stand. The squat-to-stand exercise will be done up to 10 times, and then immediately undergo echocardiographic imaging.
Amyl nitrite inhalation
Subjects will inhale amyl nitrite prior to undergoing echocardiographic imaging. This is administered according to current laboratory protocol and is part of standard of care. This is an FDA-regulated drug that will be used as a control and will not be studied experimentally.
Valsalva
Subjects will undergo echocardiographic imaging while performing the Valsalva maneuver. This is according to current laboratory protocol and is part of standard of care.
Lead Sponsor
Mayo Clinic
OTHER