Contrast-enhanced Spectral Mammography (CESM) Breast Cancer Screening

NARecruitingINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

September 19, 2019

Primary Completion Date

December 31, 2022

Study Completion Date

June 30, 2023

Conditions
Mammographic Breast DensityMammography
Interventions
DEVICE

Contrast-enhanced spectral mammography (CESM)

CESM is a mammogram performed after the injection of IV contrast. CESM is used most often when additional information is needed after a standard mammogram. CESM has also been used to determine the extent of a known breast cancer, to screen patients at high risk for developing breast cancer due to a family history or positive cancer genes, and for women with dense breast tissue. Two images are taken almost at the same time during the exam, after the iodine based contrast injection is administered. The first image is comparable to a regular mammogram. The second image shows areas that take up the contrast (enhance) showing increased blood flow. Breast cancers often enhance with contrast due to a greater amount of blood vessels. Non-cancerous lesions can also have greater blood flow.

Trial Locations (1)

22911

RECRUITING

UVA Breast Care Center, Charlottesville

All Listed Sponsors
lead

University of Virginia

OTHER