External Nitric Oxide Measurement Through SNO Degradation

NAEnrolling by invitationINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

May 10, 2021

Primary Completion Date

December 30, 2025

Study Completion Date

December 30, 2025

Conditions
HealthyUnconscious
Interventions
DEVICE

Alonefire SV003 10W 365nm UV Flashlight

Investigator will use a Nitric Oxide Analyzer while attached to a small suction port on the subject's ear lobe to be tested for Nitric Oxide. After getting the baseline assay, the investigator will shine a low-intensity UV Flashlight (Alonefire SV003 10W 365nm UV Flashlight) at the ear lobe for 10 seconds, repeated three times at 20 second intervals, to determine if there is photobleaching. Then the assay will then be performed on the opposite ear lobe. Fifteen minutes after the third UV flashlight exposure, the investigator will collect air from the subject's ear during photolysis into a 20mL glass syringe (once from each ear). Fifteen minutes after the third UV flashlight exposure, the investigator will collect air from the subject's ear during photolysis into a 20mL glass syringe (once from each ear). The subject and the investigator will wear UV goggles during the experiment.

Trial Locations (2)

46202

Riley Hospital for Children, Indianapolis

Wells Center for Pediatric Research, Indianapolis

All Listed Sponsors
lead

Indiana University

OTHER