Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/Methylcellulose

PHASE3RecruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

April 16, 2021

Primary Completion Date

June 30, 2025

Study Completion Date

December 31, 2025

Conditions
KeratoconusCorneal Ectasia
Interventions
DRUG

Riboflavin

Corneal epithelium removed followed by riboflavin drop administration (riboflavin/dextran -vs- riboflavin/methylcellulose) every 2 minutes for 30 minutes followed by UV light exposure with additional riboflavin administration every 2 minutes for 30 minutes. Subjects will be randomized to receive either the riboflavin/dextran solution or the riboflavin/HPMC solution.

Trial Locations (1)

07666

RECRUITING

Cornea and Laser Eye Institue - Hersh Vision Group, Teaneck

All Listed Sponsors
lead

Cornea and Laser Eye Institute

OTHER