A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

268

Participants

Timeline

Start Date

October 11, 2021

Primary Completion Date

March 29, 2026

Study Completion Date

April 22, 2029

Conditions
Systemic Lupus Erythematosus
Interventions
DRUG

Afimetoran

Specified dose on specified days

OTHER

Placebo

Specified dose on specified days

Trial Locations (147)

0

Local Institution - 0073, Santiago

Local Institution - 0119, Manorhamilton

404

Local Institution - 0081, Taichung

407

Local Institution - 0078, Taichung

1406

Local Institution - 0040, CABA

1425

Local Institution - 0207, Buenos Aires

1646

Local Institution - 0195, San Fernando

1878

Local Institution - 0130, Quilmes

2019

Local Institution - 0063, Botany

2145

Local Institution - 0072, Westmead

3079

Local Institution - 0064, Ivanhoe

3124

Local Institution - 0062, Camberwell

4558

Local Institution - 0066, Maroochydore

5004

Local Institution - 0025, Córdoba

5011

Local Institution - 0065, Woodville

5400

Local Institution - 0041, San Juan

10002

Local Institution - 0079, Taipei

10117

Local Institution - 0085, Berlin

10461

Local Institution - 0132, The Bronx

11030

Local Institution - 0140, Manhasset

11217

Local Institution - 0077, Taipei

11850

Local Institution - 0018, Mexico City

13003

Local Institution - 0112, Marseille

14033

Local Institution - 0144, Caen

14080

Local Institution - 0158, Mexico City

15006

Local Institution - 0056, A Coruña

20902

Local Institution - 0134, Wheaton

28009

Local Institution - 0055, Madrid

28204

Local Institution - 0203, Charlotte

28211

Local Institution - 0103, Charlotte

29609

Local Institution - 0083, Brest

30024

Local Institution - 0205, Suwanee

30318

Local Institution - 0160, Atlanta

31210

Local Institution - 0021, Chihuahua City

32174

Local Institution - 0173, Ormond Beach

32808

Local Institution - 0122, Orlando

33076

Local Institution - 0048, Bordeaux

33143

Local Institution - 0137, South Miami

33321

Local Institution - 0155, Tamarac

33324

Local Institution - 0154, Plantation

33600

Local Institution - 0156, Pessac

33765

Local Institution - 0121, Clearwater

34741

Local Institution - 0167, Kissimmee

35205

Local Institution - 0100, Birmingham

37000

Local Institution - 0020, León

39008

Local Institution - 0206, Santander

41014

Local Institution - 0057, Seville

42240

Local Institution - 0187, Hopkinsville

43203

Local Institution - 0151, Columbus

44130

Local Institution - 0042, Middleburg Heights

44650

Local Institution - 0017, Guadalajara

45070

Local Institution - 0022, Zapopan

45122

Local Institution - 0086, Essen

50937

Local Institution - 0087, Cologne

55121

Local Institution - 0070, Eagan

59037

Local Institution - 0129, Lille

60467

Local Institution - 0146, Orland Park

63110

Local Institution - 0124, St Louis

63141

Local Institution - 0165, St Louis

64000

Local Institution - 0071, Monterrey

67098

Local Institution - 0044, Strasbourg

70836

Local Institution - 0171, Baton Rouge

75013

Local Institution - 0152, Allen

Local Institution - 0197, Allen

75150

Local Institution - 0029, Mesquite

78215

Local Institution - 0163, San Antonio

79106

Local Institution - 0084, Freiburg im Breisgau

79124

Local Institution - 0136, Amarillo

83301

Local Institution - 0080, Kaohsiung Niao Sung Dist

89128

Local Institution - 0091, Las Vegas

90623

Local Institution - 0159, La Palma

91364

Local Institution - 0164, Woodland Hills

92037

Local Institution - 0170, La Jolla

92128

Local Institution - 0172, San Diego

92648

Local Institution - 0123, Huntington Beach

97070

Local Institution - 0061, Mérida

98004

Local Institution - 0223, Bellevue

100029

Local Institution - 0177, Beijing

100144

Local Institution - 0180, Beijing

110029

Local Institution - 0208, New Delhi

110221

Local Institution - 0004, Bogotá

116023

Local Institution - 0179, Dalian

122001

Local Institution - 0214, Gurugram

130000

Local Institution - 0174, Changchun

210000

Local Institution - 0176, Nanjing

210029

Local Institution - 0188, Nanjing

215006

Local Institution - 0193, Suzhou

247065

Local Institution - 0082, Râmnicu Vâlcea

250001

Local Institution - 0005, Chía

250012

Local Institution - 0178, Jinan

250252

Local Institution - 0003, Zipaquirá

272011

Local Institution - 0183, Jining

307220

Local Institution - 0068, Giroc

380015

Local Institution - 0226, Ahmedabad

500003

Local Institution - 0209, Secunderabad

518107

Local Institution - 0184, Shenzhen

560010

Local Institution - 0210, Bengaluru

760042

Local Institution - 0076, Santiago de Cali

1138431

Local Institution - 0117, Bunkyo-ku

1538515

Local Institution - 0150, Meguro-ku

1600035

Local Institution - 0098, Shinjuku-ku

1628655

Local Institution - 0105, Shinjuku-ku

1838524

Local Institution - 0218, Fuchū

2279374

Local Institution - 0143, Valdivia

5290000

Local Institution - 0127, Osorno

7500504

Local Institution - 0075, Providencia

7501126

Local Institution - 0043, Santiago

15090000

Local Institution - 0045, São José do Rio Preto

80030110

Local Institution - 0010, Curitiba

07764

Local Institution - 0219, West Long Branch

C1121ABE

Local Institution - 0074, Buenos Aires

T4000

Local Institution - 0027, San Miguel de Tucumán

C1426ABP

Local Institution - 0128, Buenos Aires

40150-150

Local Institution - 0006, Salvador

41820-020

Local Institution - 0031, Salvador

78020-500

Local Institution - 0093, Cuiabá

36010-570

Local Institution - 0008, Juiz de Fora

90480-000

Local Institution - 0007, Porto Alegre

09715-090

Local Institution - 0014, São Bernardo do Campo

04266-010

Local Institution - 0009, São Paulo

050021

Local Institution - 0190, Medellín

080020

Local Institution - 0001, Barranquilla

D15 X40D

Local Institution - 0106, Dublin

H91 TY80

Local Institution - 0107, Galway

910-1193

Local Institution - 0114, Eiheiji-cho,Yoshida-gun

807-8556

Local Institution - 0095, Kitakyushu

060-8648

Local Institution - 0096, Sapporo

920-8641

Local Institution - 0104, Kanazawa

980-8574

Local Institution - 0099, Sendai

173-8610

Local Institution - 0113, Itabashiku

457-8511

Local Institution - 0138, Aichi

260-8712

Local Institution - 0115, Chiba

960-1295

Local Institution - 0162, Fukushima

104-8560

Local Institution - 0097, Tokyo

113-8654

Local Institution - 0116, Tokyo

06760

Local Institution - 0060, Mexico City

02-665

Local Institution - 0204, Warsaw

60-218

Local Institution - 0049, Poznan

00-874

Local Institution - 0149, Warsaw

50-556

Local Institution - 0052, Wroclaw

00917

Local Institution - 0037, San Juan

011053

Local Institution - 0157, Bucharest

011172

Local Institution - 0067, Bucharest

08035

Local Institution - 0058, Barcelona

CB2 2QQ

Local Institution - 0111, Cambridge

BD5 0NA

Local Institution - 0110, Bradford

M13 9WL

Local Institution - 0125, Manchester

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY