Cognitive Effects of Adjuvant Vortioxetine in Early Schizophrenia

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

January 20, 2022

Primary Completion Date

December 20, 2024

Study Completion Date

December 20, 2025

Conditions
Cognitive Impairment With Primary Psychotic DisorderNegative Symptoms With Primary Psychotic Disorder
Interventions
DRUG

Vortioxetine

"First treatment phase: vortioxetine will be initiated at 10 mg / day for 2 weeks, followed by 20 mg /day for 22 weeks. The dose of vortioxetine can be lowered to 5 mg or 10 mg for tolerability reasons at clinician criteria.~Wash-out period 2 weeks"

DRUG

Usual Antipsychotic Treatment

Second treatment phase. Usual antipsychotic treatment for 26 weeks: Allows for whatever medication, routine support, or referral to other services was felt appropriate by the clinician.

Trial Locations (1)

41013

RECRUITING

Hospital Universitario Virgen del Rocío, Seville

All Listed Sponsors
lead

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

OTHER