Hormonal Influences on Diuresis

NACompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

May 1, 2015

Primary Completion Date

September 30, 2018

Study Completion Date

September 30, 2018

Conditions
NocturiaMenopauseLUTSDiuresis
Interventions
DIAGNOSTIC_TEST

ICIQ FLUTS Questionaires

Questionnaire observing the impact on voiding disfunctions

DIAGNOSTIC_TEST

Frequency Volume Chart

Frequency Volume Chart measures the voided volumes and fluid intake during 3 days in order to observe patients bladder capacity, total and nighttime voided volume and voiding frequency

DIAGNOSTIC_TEST

Renal Function Profile

The RFP is a 24-hour urine analysis in which urine samples are collected at fixed time points every 3 hours, starting 3 hours after the first morning void. This RFP was collected on a separated day to the FVC. Daytime samples were taken between 10:00-11:30 (U1), 13:00-15:30 (U2), 16:00-17:30 (U3), 19:00-20:30 (U4), and 22:00-23:30 (U5). The night-time samples were taken between 1:00-2:30 (U6), 4:00-5:30 (U7) and 7:00-8:30 (U8), and the volume of each interim void, was noted to calculate the 24h, daytime and night-time urine volume and diuresis rate. On each of this 8 samples, creatinine, osmolality, sodium and urea concentration were analysed. Subsequently, the renal clearance of creatinine, solutes, sodium and potassium (Usubst x Uflow / Psubst) and FWC (urine flow - solute clearance) were calculated.

DIAGNOSTIC_TEST

Blood Analysis

Blood analysis in order to observ postmenopausal state, osmolalitity and sodium.

All Listed Sponsors
lead

University Hospital, Ghent

OTHER

NCT04891926 - Hormonal Influences on Diuresis | Biotech Hunter | Biotech Hunter