Factors That Influence Blood Vessel Regulation During Exercise in Humans

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 20, 2021

Primary Completion Date

November 15, 2022

Study Completion Date

November 15, 2022

Conditions
Ischemic PreconditioningDietary Exposure
Interventions
PROCEDURE

Ischemic preconditioning

Four 5-minute cycles of 200 mmHg cuff inflation of the brachial artery, each separated by 5-minutes deflated recovery (i.e. 40 minutes total time)

PROCEDURE

Ischemic preconditioning control

Four 5-minute cycles of 20 mmHg cuff inflation of the brachial artery, each separated by 5-minutes deflated recovery (i.e. 40 minutes total time)

DIETARY_SUPPLEMENT

Low fat meal

Meal containing 1006 calories, 1 g fat, 0.2 g saturated fat, 0 g trans fat, 20 mg cholesterol, 191 g carbohydrates, 60 g protein, 1560 mg sodium

DIETARY_SUPPLEMENT

High fat meal

Meal containing 1030 calories, 62 g fat, 23 g saturated fat, 0.5 g trans fat, 445 mg cholesterol, 76 g carbohydrates, 41 g protein, 2080 mg sodium.

Trial Locations (1)

N1G 2W1

University of Guelph - Human Cardiovascular Physiology Laboratory, Guelph

All Listed Sponsors
lead

University of Guelph

OTHER