146
Participants
Start Date
March 28, 2022
Primary Completion Date
August 15, 2023
Study Completion Date
August 15, 2023
Virtual reality
Subjects in the virtual reality group will be offered a variety of immersive environments to choose from (mountains, beach, rainforest and temperate forest) in addition to local anesthetic.
Intravenous sedation
Sedation will be administered using low-dose midazolam and/ or fentanyl. We will use a wide range of dosing (1-5 mg for midazolam, up to 150 mcg for fentanyl) to maximize generalizability and account for widespread variability in clinical circumstances, medical practice and patient response (personalized medicine). Sedation will be titrated to effect by a board-certified or eligible anesthesiologist so that patients remain responsive to verbal stimuli.
Standard care
Patients will receive superficial local anesthetic with 1% lidocaine. Local anesthetic will be administered by the physician performing the procedure titrated to patient comfort.
Johns Hopkins Medical Institutions, Baltimore
United States Department of Defense
FED
The Geneva Foundation
OTHER
Walter Reed National Military Medical Center
FED
United States Naval Medical Center, San Diego
FED
Brigham and Women's Hospital
OTHER
Johns Hopkins University
OTHER