PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Sitravatinib is a small molecule inhibitor of receptor tyrosine kinases

CYP2C9 probe substrate

CYP2D6 probe substrate

CYP3A4 probe substrate

P-gp probe substrate

BCRP probe substrate

Nivolumab is a programmed death receptor (PD-1) blocking antibody