Deep Brain Stimulation for Parkinson's Disease: Probabilistic STN Targeting Under General Anaesthesia Without Micro-electrode Recordings vs Current Targeting Procedure

NAActive, not recruitingINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

November 10, 2021

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Parkinson Disease
Interventions
PROCEDURE

Surgery under general anesthesia with experimental targeting

Surgery will be performed under general anesthesia. The electrodes will be inserted directly on the targets without MER, with PARKEO\_2 targets provided by the Bordeaux University Hospital, based on the machine-learning model developed in Bordeaux.

PROCEDURE

Usual Surgery

In the control group, surgery will be performed as usual in each centre under local or general anaesthesia. This group represents the current state of the art of deep brain stimulation in these centres.

Trial Locations (10)

13005

CHU Marseille, Marseille

Unknown

CHU Amiens, Amiens

CHU de Bordeaux, Bordeaux

CHU Grenoble, Grenoble

Hospices Civils de Lyon, Lyon

CHRU de Nancy, Nancy

CHU de Nice, Nice

CHU de Rouen, Rouen

CHU de Strasbourg, Strasbourg

CHU de Toulouse, Toulouse

All Listed Sponsors
lead

University Hospital, Bordeaux

OTHER