Prevention of Mild-to-moderate Hypoglycemia in Type 1 Diabetes

Participants will be admitted at the research center at 7:00 after an overnight fast. A venous catheter will be inserted into an arm vein for blood sampling purposes. A subcutaneous insulin bolus will be administered to bring plasma glucose to the glycemic threshold. Oral carbohydrates (16g) will be given when plasma glucose levels are at the target threshold. Sixty minutes after carbohydrates consumption, a standardized meal will be provided and participants will be discharged 90 minutes after the meal.

Participants will have to wear a Dexcom G6 during study interventions

When the glycemic threshold is reach, participants will be given 16g of Dex4

A subcutaneous insulin bolus will be given to induce a decline in plasma glucose and reach the glycemic threshold.