Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer

NARecruitingINTERVENTIONAL
Enrollment

416

Participants

Timeline

Start Date

July 13, 2020

Primary Completion Date

January 1, 2027

Study Completion Date

January 1, 2027

Conditions
Colon Cancer
Interventions
PROCEDURE

Conventional Right hemicolectomy (Non-CME)

Transecting the Ileocolic Vein and Artery close to the Superior Mesenteric Vessels without clearing the superior mesenteric vein (SMV) from the adipose tissue. Transecting the Right Colic Vein and Artery and superior right colic vein (when present) peripherally. Transecting the Right branches of the Middle Colic Vein (MCV) and the Middle Colic Artery (MCA) peripherally, without clearing the main trunk of the MCV and the MCA. The Right Gastroepiploic Vein and artery are never transacted.

PROCEDURE

Right hemicolectomy with CME+CVL

"Separation of the visceral fascia from the parietal fascia by sharp dissection leaving intact mesocolon coverage. Transecting the supplying vessels at their origin from the main vessels, particularly:~* The Ileocolic Vessels, The Right Colic Vessels,The superior right colic vein (when present), The Right branches of the Middle Colic Vein and of the Middle Colic Artery~* The MCV and MCA at their origin in case of cancer of the hepatic flexure or of the proximal third of the transverse colon, as well as The Right Gastroepiploic Vessels at their origin from the gastrocolic trunk of Henle (GCTH) and the gastroduodenal artery.~The SMV should be cleared from all adipose tissue all along its anterior surface until its intrapancreatic entrance."

Trial Locations (14)

10043

RECRUITING

University of Turin (AOU.San Luigi Gonzaga), Torino

10060

NOT_YET_RECRUITING

Candiolo Cancer Institute - IRCCS, Candiolo

10064

NOT_YET_RECRUITING

Ospedale E. Agnelli Pinerolo, Pinerolo

16132

NOT_YET_RECRUITING

Ospedale Policlinico San Martino, Genova

19121

NOT_YET_RECRUITING

S. Andrea Hospital, La Spezia

20099

NOT_YET_RECRUITING

Ospedale Città di Sesto San Giovanni, Sesto San Giovanni

20141

NOT_YET_RECRUITING

European Institute of Oncology, Milan

40124

NOT_YET_RECRUITING

Maggiore Bellaria Hospital, Bologna, Bologna

44121

NOT_YET_RECRUITING

Università degli Studi di Ferrara, Ferrara

52100

NOT_YET_RECRUITING

Ospedale della Misericordia, Grosseto

80138

NOT_YET_RECRUITING

Federico II University, Napoli

98124

NOT_YET_RECRUITING

"Azienda Ospedaliera Universitaria Policlinico G. Martino", Messina

00133

NOT_YET_RECRUITING

University of Rome Tor Vergata, Rome

00168

NOT_YET_RECRUITING

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome

All Listed Sponsors
collaborator

Federico II University

OTHER

collaborator

Agnelli Hospital, Italy

OTHER

collaborator

Ospedale della Misericordia

OTHER

collaborator

Candiolo Cancer Institute - IRCCS

OTHER

collaborator

Maggiore Bellaria Hospital, Bologna

OTHER

collaborator

Università degli Studi di Ferrara

OTHER

collaborator

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

collaborator

"Azienda Ospedaliera Universitaria Policlinico G. Martino"

OTHER

collaborator

Ospedale Policlinico San Martino

OTHER

collaborator

University of Rome Tor Vergata

OTHER

collaborator

S. Andrea Hospital

OTHER

collaborator

European Institute of Oncology

OTHER

lead

University of Turin, Italy

OTHER