Dexmedetomidine and Myocardial Protection

NAActive, not recruitingINTERVENTIONAL
Enrollment

224

Participants

Timeline

Start Date

July 7, 2021

Primary Completion Date

December 30, 2024

Study Completion Date

December 30, 2025

Conditions
Cardiac SurgeryCardiopulmonary Bypass
Interventions
DRUG

Dexmedetomidine

"Anesthesia is induced using midazolam or etomidate, and sufentanil. A target-controlled infusion of propofol and remifentanil is used for anesthesia maintenance.~From anesthesia induction before the initiation of cardiopulmonary bypass, dexmedetomidine is infused intravenously at a rate of 0.5 mcg/kg/hr after a loading dose infusion of 0.75 mcg/kg for 10 mins."

DRUG

Control

During the same time window for dexmedetomidine, normal saline is infused at the same rate calculated for dexmedetomidine.

Trial Locations (1)

03080

Seoul National University Hospital, Seoul

All Listed Sponsors
lead

Seoul National University Hospital

OTHER