Pharmacokinetics of Voriconazole in Adult ECMO Patients

RecruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

August 24, 2021

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
AspergillosisInfluenzaCovid19
Interventions
OTHER

5 blood samples

5 blood samples across 3 occasions/sampling windows (Day 1-4, Day 6-9 and Day 11-14) to determine plasma concentrations of voriconazole

GENETIC

Determination of CYP2C19 genotype

A single buccal swab to determine the CYP2C19 genotype will be undertaken during the course of ICU stay.

Trial Locations (1)

Unknown

RECRUITING

University Hospitals of Leicester, Leicester

All Listed Sponsors
lead

University Hospitals, Leicester

OTHER