Clinical Outcome and Future Liver Remnant Regenerative Response in Laparoscopic Versus Open ALPPS

PHASE3RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 2, 2020

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2027

Conditions
Liver Cancer
Interventions
PROCEDURE

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a surgical procedure that induces rapid liver regeneration in patients with small liver remnant planning for major liver resection. It is a two-staged operation with stage I including portal vein ligation and splitting the right liver away from the left liver. After stage I, the left liver will undergo rapid liver regeneration and the stage II operation can be performed at 7-10 days after stage I operation when the liver remnant reaches an adequate size. In stage II operation, the right liver that contains the tumor is then removed.

Trial Locations (1)

Unknown

RECRUITING

The University of Hong Kong, Hong Kong

All Listed Sponsors
lead

The University of Hong Kong

OTHER

NCT04868149 - Clinical Outcome and Future Liver Remnant Regenerative Response in Laparoscopic Versus Open ALPPS | Biotech Hunter | Biotech Hunter