Photodynamic Therapy for Cholangiocarcinoma

NACompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

April 17, 2021

Primary Completion Date

November 19, 2024

Study Completion Date

November 19, 2024

Conditions
Cholangiocarcinoma Non-resectable
Interventions
DRUG

Hematoporphyrin

Patients with negative skin test of hematoporphyrin Injection (3.0-5.0mg/Kg plus saline 250 mL intravenous drip, the drip was completed within 1 hour) and keep patients away from the light. The first PDT therapy was performed 24 hours after infusion of hematoporphyrin injection by ERCP. The biliary tumor necrosis was observed and the biliary tract was cleaned up 24 hours later and then PDT therapy showed again if necessary. Multiple plastic stents or bald metal stents will be placed. Follow up regularly after the procedure, PDT therapy would be given again in 3 months.

Trial Locations (11)

130021

The First Hospital of Jilin University, Changchun

200092

Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai

250000

Shandong Provincial Third Hospital, Jinan

400038

Southwest Hospital, Army Medical University, Chongqing

430022

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

510260

The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou

710061

The first affiliated hospital of Xi 'an JiaoTong university, Xi'an

730000

The First Hospital of Lanzhou University, Lanzhou

750004

General Hospital of Ningxia Medical University, Yingchuan

830054

The First Affiliated Hospital of Xinjiang Medical University, Ürümqi

030008

General Hospital of Taiyuan Iron and Steel Corporation, Taiyuan

All Listed Sponsors
lead

Hepatopancreatobiliary Surgery Institute of Gansu Province

OTHER