NCT04859283View on ClinicalTrials.gov

Premedication with Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty

PHASE4CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 10, 2022

Primary Completion Date

September 15, 2023

Study Completion Date

January 20, 2025

Conditions
Knee OsteoarthritisPain, Postoperative
Interventions
DRUG

Dexmedetomidine

Intranasal dexmedetomidine 1µg/kg will be administered 30min before the induction of anesthesia using a LMA MAD Nasal-device

DRUG

Placebo

Intranasal saline (10 µL/kg) will be administered 30 min before the induction of anesthesia using a LMA MAD NasalTM -device. The dose is euvolemic to 1 µg/mL dexmedetomidine.

Trial Locations (1)

Unknown

Perioperative Services, Intensive Care and Pain Therapy, Turku University Hospital and University of Turku, Turku

All Listed Sponsors
lead

Turku University Hospital

OTHER_GOV