Study of RP-6306 Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

364

Participants

Timeline

Start Date

April 30, 2021

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Advanced Solid Tumor
Interventions
DRUG

RP-6306

Oral PKMYT1 Inhibitor

DRUG

RP-3500

Oral ATR Inhibitor

DRUG

Debio0123

Oral WEE1 Inhibitor

Trial Locations (22)

10032

ACTIVE_NOT_RECRUITING

#1008, Columbia University, New York

10065

RECRUITING

#1004, Memorial Sloan Kettering Cancer Institute, New York

11042

RECRUITING

#1032, Northwell Health Cancer Institute, New Hyde Park

19104

COMPLETED

#1010, University of Pennsylvania, Philadelphia

22903

RECRUITING

#1027, University of Virginia, Charlottesville

32224

RECRUITING

#1017, Mayo Clinic, Jacksonville

49503

RECRUITING

#1023, START Midwest, Grand Rapids

63130

RECRUITING

#1011, Washington University, St Louis

77030

RECRUITING

#1001, The University of Texas M.D. Anderson Cancer Center, Houston

84112

RECRUITING

#1013, The University of Utah, Salt Lake City

85054

RECRUITING

#1016, Mayo Clinic, Phoenix

90095

COMPLETED

# 1019, UCLA, Westwood Cancer Center, Los Angeles

94158

RECRUITING

#1025, University of California San Francisco, San Francisco

06520

RECRUITING

#1012, Yale, New Haven

02215

RECRUITING

#1002, Dana Farber Cancer Institute, Boston

02903

RECRUITING

#1007, Rhode Island Hospital, Providence

RECRUITING

#1030, Women & Infants Hospital of Rhode Island, Providence

M5G 1X8

COMPLETED

#2002, The Hospital for Sick Children, Toronto

M5G 2C1

RECRUITING

#2001, Princess Margaret Cancer Centre, Toronto

H4A 3J1

COMPLETED

#2003, The Research Institute of the McGill University Health Centre, Montreal

Unknown

RECRUITING

#4001, Rigshospitalet - Blegdamsvej, Copenhagen

W1G 6AD

RECRUITING

#3003, Sarah Cannon Research Institute, London

Sponsors
All Listed Sponsors
collaborator

Debiopharm International SA

INDUSTRY

lead

Repare Therapeutics

INDUSTRY