Reward Emotion Learning and Ketamine Study

NAUnknownINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

August 25, 2021

Primary Completion Date

May 31, 2023

Study Completion Date

May 31, 2023

Conditions
DepressionMajor Depressive DisorderTreatment Resistant Depression
Interventions
DRUG

Ketamine Hydrochloride

Ketamine is a high trapping NMDA receptor antagonist which has rapid and reliable antidepressant effects in patients with major depressive disorder (MDD) who have failed to respond to conventional monoaminergic agents.

OTHER

No intervention (placebo)

Placebo injection (0.9% sodium chloride)

Trial Locations (1)

OX3 7JZ

RECRUITING

University of Oxford, Oxford

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medical Research Council

OTHER_GOV

collaborator

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

INDUSTRY

lead

University of Oxford

OTHER