Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness

PHASE1CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

August 11, 2021

Primary Completion Date

March 27, 2023

Study Completion Date

March 27, 2023

Conditions
Healthy
Interventions
DRUG

Placebo

Drug: Placebo Capsules containing mannitol looking identical to the other drugs Other: Placebo Capsules containing mannitol looking identical to the other drugs

DRUG

Mescaline 100mg

"Drug: 100mg Mescaline per os, single dose~Other: Placebo (Capsules containing mannitol looking identical to the other drugs)"

DRUG

Mescaline 200mg

"Drug: 200mg Mescaline per os, single dose~Other: Placebo (Capsules containing mannitol looking identical to the other drugs)"

DRUG

Mescaline 400mg

"Drug: 400mg Mescaline per os, single dose~Other: Placebo (Capsules containing mannitol looking identical to the other drugs)"

DRUG

Mescaline 800mg

"Drug: 800mg Mescaline per os, single dose~Other: Placebo (Capsules containing mannitol looking identical to the other drugs)"

DRUG

Mescaline 800mg + Ketanserin 40mg

"Drug: 800mg Mescaline per os, single dose~Other: 40mg Ketanserin per os, single dose"

Trial Locations (1)

4056

University Hospital Basel, Clinical Trial Unit, Basel

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER

NCT04849013 - Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness | Biotech Hunter | Biotech Hunter