NCT04845490 - Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy | Biotech Hunter

Enrollment

201

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

September 1, 2023

Study Completion Date

September 1, 2026

Conditions

Colorectal CancerChemotherapy EffectSurgeryMetastasisSurvival

Interventions

DRUG

Mitomycin

Mitomycin is used as drug for hyperthermic intraperitoneal chemotherapy. Choice of perfusate: Normal saline. Drug selection and dose: Mitomycin 30mg/m2. Treatment course: 2 times (the first time is after surgery, the second time is 48h after first time).

DRUG

Lobaplatin

Lobaplatin is used as drug for hyperthermic intraperitoneal chemotherapy. Choice of perfusate: Normal saline. Drug selection and dose: Lobaplatin 50mg/m2. Treatment course: 2 times (the first time is after surgery, the second time is 48h after first time).

All Listed Sponsors

lead

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER