NCT04845035 - Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia | Biotech Hunter

Timeline

Start Date

January 31, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2029

Conditions

Acute Lymphoblastic Leukemia

Interventions

DRUG

Dasatinib

By mouth

DRUG

Ponatinib

By mouth

DRUG

Berlin-Frankfurt-Münster Chemotherapy

with varied cycles, including Daunorubicin, Vincristine, Prednisone, Pegaspargase, Rituximab, Cytarabine, Mercaptopurine, Cyclophosphamide, Methotrexate, Doxorubicin, Thioguanine, and Dexamethasone

DRUG

Methotrexate and Cytarabine

Intrathecal

Trial Locations (1)

48109

University of Michigan Rogel Cancer Center, Ann Arbor