NCT04843566 - PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy | Biotech Hunter

Enrollment

687

Participants

Timeline

Start Date

March 22, 2021

Primary Completion Date

April 19, 2024

Study Completion Date

April 19, 2024

Conditions

Infection

Interventions

PROCEDURE

Transperineal MRI-guided prostate biopsy

Transperineal prostate biopsy will be performed under local anesthesia in the office. This approach avoids transrectal needle tracking.

PROCEDURE

Transrectal MRI-guided prostate biopsy

Transrectal prostate biopsy is currently the most popular approach to evaluate a positive screening test for prostate cancer.

DRUG

Antibiotic (prophylaxis)

"For men undergoing transrectal biopsy, antibiotic prophylaxis will be administered in accordance with guidelines from the American Urological Association (AUA).~No antibiotic prophylaxis will be administered for men undergoing transperineal biopsy."

Trial Locations (10)

10065

Memorial Sloan Kettering Cancer Center, New York

Weill Cornell Medicine, New York

11217

NewYork Presbyterian Brooklyn Methodist Hospital, Brooklyn

11355

NewYork-Presbyterian Queens, Flushing

20007

Georgetown University, Washington D.C.

21287

Johns Hopkins University, Baltimore

44106

University Hospitals Cleveland Medical Center, Cleveland

60611

Northwestern University, Chicago

06030

University of Connecticut, Farmington

48109-5624

University of Michigan Medical School, Ann Arbor

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

Weill Medical College of Cornell University

OTHER