ERASE VITILIGO Early Repigmentation Approach for Stopping the Evolution of VITILIGO Prospective Multicentric Interventional Study With Blinded Evaluation

NACompletedINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

June 1, 2021

Primary Completion Date

October 10, 2024

Study Completion Date

August 18, 2025

Conditions
Vitiligo
Interventions
OTHER

The resident memory T-cell infiltrate in perilesional vitiligo skin

"The 3 groups will receive a combination of narrowband UVB (Nb-UVB) 3 times a week and oral mini pulses of systemic steroids (5 mg of d medrol 16mg twice a week) for 24 weeks.~Three visits will be done (inclusion, Week 12 and 24) A skin biopsy will be done on lesional and peri-lesional area at baseline. Another skin biopsy will be taken after 24 weeks but only in perilesional area. A blood sample for assessing the circulating memory T cells and for checking the tolerance will be performed at baseline, then at W12 and W24."

Trial Locations (2)

33440

CHU Bordeaux, Bordeaux

06001

CHU de Nice, Nice

All Listed Sponsors
lead

Centre Hospitalier Universitaire de Nice

OTHER