A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea,

NARecruitingINTERVENTIONAL
Enrollment

185

Participants

Timeline

Start Date

September 22, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Chondral DefectArticular Cartilage DefectArticular Cartilage Disorder of Knee
Interventions
DEVICE

JointRep®

JointRep® is a medical device based on a thermogel polymer (Chitosan) for the treatment of chondral lesions, which consists of an injectable aqueous composition that forms a solid and sticky hydrogel in situ within cartilage defect(s). JointRep® is composed of an injectable thermo-gelling aqueous composition. It is used in conjunction with a Bone Marrow Stimulation type of procedure like Microfracture.

PROCEDURE

Microfracture

Microfracture is a bone marrow stimulation type of procedure where after debridement of the damaged chondral tissue within the lesion, obtention of stable vertical margins and curettage of the entire calcified layer, multiple holes are created with a variety of instruments (awls, picks, microdills, nanofracture) to establish a communication with the subchondral bone to create a blood clot to elicit the natural healing process

Trial Locations (8)

Unknown

RECRUITING

Canberra Orthopaedics and Sports Medicine, Deakin

ACTIVE_NOT_RECRUITING

Sydney Knee Specialists, Kogarah

RECRUITING

Lingard Private Hospital, Newcastle

RECRUITING

Orthosports, Randwick

RECRUITING

Cairns Orthopaedic Clinic, Parramatta Park

RECRUITING

North Queensland Knee, Pimlico

RECRUITING

Melbourne Orthopedic Group, Melbourne

B2Y 4G8

RECRUITING

Dartmouth General Hospital, Dartmouth

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mobius Medical Pty Ltd.

INDUSTRY

lead

Oligo Medic Pty Ltd

INDUSTRY

NCT04840147 - A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea, | Biotech Hunter | Biotech Hunter