NCT04837768View on ClinicalTrials.gov

Effect of Intramuscular Progesterone Supplementation on Clinical and Ongoing Pregnancy Rates in Patients With Low Serum Progesterone Levels on the Day of Embryo Transfer in Artificial Frozen Cycles

NACompletedINTERVENTIONAL
Enrollment

354

Participants

Timeline

Start Date

July 27, 2021

Primary Completion Date

March 1, 2022

Study Completion Date

March 15, 2022

Conditions
Serum Progesterone LevelsProgesterone SupplementationFrozen Embryo TransferClinical Pregnancy RatesOngoing Pregnancy Rates
Interventions
DRUG

Twice-daily transvaginal progesterone supplementation

Patients with serum progesterone levels \>9.2 ng/ml on the day of embryo transfer in artificial frozen cycles will receive the traditional twice-daily vaginal progesterone supplementation till 12 weeks gestation.

DRUG

Twice-weekly intramuscular + Twice-daily transvaginal progesterone supplementation

Patients with serum progesterone levels \<9.2 ng/ml on the day of embryo transfer in artificial frozen cycles will receive the twice-daily vaginal progesterone in addition to twice-weekly intramuscular progesterone supplementation till 12 weeks gestation.

Trial Locations (2)

11956

Cairo University, Faculty of Medicine, Department of Obstetrics and Gynecology, Cairo

12611

AlBoshra IVF & Infertility Treatment Centre, Cairo

All Listed Sponsors
lead

Cairo University

OTHER

NCT04837768 - Effect of Intramuscular Progesterone Supplementation on Clinical and Ongoing Pregnancy Rates in Patients With Low Serum Progesterone Levels on the Day of Embryo Transfer in Artificial Frozen Cycles | Biotech Hunter | Biotech Hunter