"Deficit in Quadriceps Voluntary Activation After Anterior Cruciate Ligament Reconstruction: Roles of the Learned Non-use Paradigm and the Interhemispheric Inhibition"

RecruitingOBSERVATIONAL
Enrollment

10

Participants

Timeline

Start Date

July 14, 2021

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Anterior Cruciate Ligament Injuries
Interventions
DIAGNOSTIC_TEST

Pathologic group

"Voluntary Activation level will be determined with the interpolate twitch technique (ITT), both during isometric contractions (knee at 40° flexion) and during isokinetic contraction at angular velocity equal to 100°/s.~Vastus Medialis and Soleous H-reflex will be measured. Cortical excitability and interhemispheric connectivity will be measured through transcranial magnetic stimulation (TMS).~Tests of balance in standing will be performed using the EquiTest platform. Individuals will be requested to perform three different tasks: Sensory Organization test, Adaptation Test upward/downward, Motor Control test backward/forward. Surface electromyography from lower limbs will be recorded.~Through TMS driven by neuronavigation, the cortical representation of the Quadriceps muscle will be studied.~Gait analysis will be performed on a treadmill mounted on force sensors. Participants will walk at increasing velocities from 0.4 m/s to 1.6 m/s. Speed will be increased of 0.2 m/s every 30 s."

Trial Locations (2)

20121

RECRUITING

Istituto Auxologico Italiano, Milan

Unknown

NOT_YET_RECRUITING

ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Presidio Ospedaliero Gaetano Pini, Milan

All Listed Sponsors
collaborator

ASST Gaetano Pini-CTO

OTHER

lead

Istituto Auxologico Italiano

OTHER