Letrozole Versus Gonadotropins in Clomiphene Citrate Resistance

PHASE4CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

March 1, 2019

Primary Completion Date

October 31, 2019

Study Completion Date

October 31, 2019

Conditions
Clomiphene Citrate ResistanceOvulation InductionLetrozoleGonadotropins
Interventions
DRUG

Letrozole 2.5mg

These patients were treated with letrozole (Femara®, Novartis New York, NY, USA) in a dose 2.5 mg (one tablet daily) orally began on the 3rd day to the 7th day of the cycle. If ovulation is not achieved dose is increased by 2.5 mg in next cycle till 3 cycles

DRUG

Gonadotropin

These patients were given urofollitropin (fostimon ®, IBSA, Lugano, Switzerland) in a dose of 75 IU/mL I.M from day 3rd to day 7th of the cycle beginning by one ampoule per day and the dose had been modulated according to response.

Trial Locations (1)

31111

Ayman Shehata Dawood, Tanta

All Listed Sponsors
lead

Tanta University

OTHER

NCT04834791 - Letrozole Versus Gonadotropins in Clomiphene Citrate Resistance | Biotech Hunter | Biotech Hunter