UA Versus UAE in Treatment of Fibroids

PHASE4CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

March 13, 2019

Primary Completion Date

March 13, 2021

Study Completion Date

March 13, 2021

Conditions
Uterine Fibroid
Interventions
DRUG

Ulipristal Oral Tablet

A selective progesterone receptor modulator (SPRM), as a medical line of treatment for uterine fibroids. Due to its selective anti-proliferative and pro-apoptotic action, Ulipristal Acetate (UA) is assumed to be effective in reducing abnormal uterine bleeding (AUB) and fibroid size.

PROCEDURE

Uterine artery embolization

Selective embolization of uterine arteries bilaterally, using polyvinyl alcohol (PVA) particles administered via a catheter followed by capping with a plug of gelatin sponge. The end point for embolization is to have a static column of contrast in the uterine artery, with only a stump filling when the internal iliac artery was injected.

Trial Locations (1)

11517

Ain Shams Maternity Hospital, Cairo

All Listed Sponsors
lead

Ain Shams Maternity Hospital

OTHER

NCT04832906 - UA Versus UAE in Treatment of Fibroids | Biotech Hunter | Biotech Hunter