NCT04825743 - A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI | Biotech Hunter

Enrollment

2,463

Participants

Timeline

Start Date

April 24, 2021

Primary Completion Date

May 13, 2026

Study Completion Date

May 13, 2026

Conditions

ST-elevation Myocardial Infarction (STEMI)

Interventions

DRUG

zalunfiban

zalunfiban is a novel small molecule inhibitor of the platelet αIIbβ3 receptor specifically designed for first medical contact therapy of ST-elevation myocardial infarction (STEMI).

DRUG

Placebo

A placebo will be prepared to those subjects assigned to placebo. Less than 1 mL (depending on subject's weight) will be administered by subcutaneous injection.

Trial Locations (45)

14080

"Instituto Nacional de Cardiologia Ignacio Chavez", Mexico City

48073

Corewell Health William Beaumont University Hospital, Royal Oak

63110

Washington University, St Louis

75390

UT Southwestern Medical Center, Dallas

77030

Baylor College of Medicine, Houston

92100

Hospital Ambroise Pare, Boulogne-Billancourt

99508

Providence Alaska Medical Center, Anchorage

Unknown

University of Alberta, Edmonton

St. Anne's University hospital, Brno

University Hospital Brno, Brno

European Hosital de Paris - GVM Care & Research (La Roseraie), Aubervilliers

Henri Mondor University Hospital, Créteil

Grenoble Alpes University Hospital, Grenoble

University Hospital of Marseille - La Timone Hospital, Marseille

André Grégoire Hospital - GHT GPNE, Montreuil

Bichat-Claude Bernard Hospital, Paris

Hôpital Cochin, Paris

Lariboisière Hospital AP-HP, Paris

University Hospital De La Pitié-Salpêtrière, Paris

Regional University Hospital of Rennes - Hospital Ponchaillou, Rennes

Semmelweis University Heart and Vascular Center, Budapest

Bacs-Kiskun County Teaching Hospital, Kecskemét

Zuyderland MC, Heerlen

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch

Amsterdam UMC, locatie AMC, Amsterdam

Amsterdam UMC, Amsterdam

Rijnstate Arnhem, Arnhem

Tergooi Blaricum, Blaricum

Amphia Ziekenhuis, Breda

Slingeland Ziekenhuis, Doetinchem

Ziekenhuis Gelderse Vallei, Ede

Medisch Spectrum Twente, Enschede

Leiden University Medical Center, Leiden

Maastricht UMC, Maastricht

ETZ TweeSteden, Tilburg

UMC Utrecht, Utrecht

Viecuri Medisch Centrum, Venlo

Isala, Zwolle

"Emergency Clinical Hospital Bagdasar-Arseni, Bucharest", Bucharest

Emergency University Hospital Bucharest, Bucharest

"Institute of Cardiovascular Diseases Prof. George I.M. Georgescu Iasi", Iași

Emergency Clinical County Hospital Targu-Mures, Târgu Mureş

Institute for Cardiovascular Diseases Timisoara, Timișoara

H4032

University of Debrecen, Debrecen

3435 CM

St. Antonius Ziekenhuis, Nieuwegein