NCT04823715View on ClinicalTrials.gov

Transarterial Chemoembolization Plus Hypofractionnated Radiotherapy vs. Surgery in Locally Advanced Hepatocellular Carcinoma: an IPTW Comparison

CompletedOBSERVATIONAL
Enrollment

163

Participants

Timeline

Start Date

October 15, 2020

Primary Completion Date

January 15, 2021

Study Completion Date

January 15, 2021

Conditions
Non-metastatic Hepatocellular Carcinoma
Interventions
OTHER

TACE + hypofractionated EBRT

One cure of doxorubicin or DC Beads transarterial chemoembolization by a highly experienced interventional radiologist, followed 1 to 4 weeks later by hypofractionated external beam radiation therapy up to a total dose of 45-60 Gy, 3 Gy per fraction, 5 fractions per week, for an overall treatment time of 3 to 4 weeks.

PROCEDURE

Surgical resection

Surgical resection by open-laparotomy or laparoscopy of hepatocellular carcinoma by a highly experienced liver surgeon

Trial Locations (1)

69004

Croix-Rousse Hospital, Hospices Civils de Lyon, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT04823715 - Transarterial Chemoembolization Plus Hypofractionnated Radiotherapy vs. Surgery in Locally Advanced Hepatocellular Carcinoma: an IPTW Comparison | Biotech Hunter | Biotech Hunter