Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma

NACompletedINTERVENTIONAL
Enrollment

236

Participants

Timeline

Start Date

July 19, 2021

Primary Completion Date

May 15, 2025

Study Completion Date

May 15, 2025

Conditions
Nasopharyngeal CarcinomaNutritional Support
Interventions
DIETARY_SUPPLEMENT

Abbott®Ensure

Abbott®Ensure: 55.8 g each time, three times a day, from the beginning to the end of radiotherapy

RADIATION

Intensity Modulated Radiation Therapy

The prescribed dose was 68-76 Gy to Planning target volume of the primary tumor (PTVnx), 66-70 Gy to Planning target volume of the cervical lymph node (PTVnd), 60-64 Gy to planning target volume 1 (PTV1), and 50-54 Gy to planning target volume 2 (PTV2) in 30-33 fractions. The details of dose limits for organs at risk were based on the study 0225 from The Radiation Therapy Oncology Group (RTOG 0225).

DRUG

cisplatin

80-100 mg/m² cisplatin given intravenously every 3 weeks concurrently with radiotherapy.

Trial Locations (13)

330029

Jiangxi Provincial Cancer Hospital, Nanchang

350001

Fujian Medical University Union Hospital, Fuzhou

350005

First Affiliated Hospital of Fujian Medical University, Fuzhou

350014

Fujian Cancer Hospital, Fuzhou

350025

900th hospital of the joint logistics team, PLA, Fuzhou

353000

The Nanping First Affiliated Hospital of Fujian Medical University, Nanping

361003

The First Affiliated Hospital of Xiamen University, Xiamen

361004

Zhongshan Hospital Xiamen University, Xiamen

362000

Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou

The Second Affiliated Hospital of Fujian Medical University, Quanzhou

363000

Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou

410013

Hunan Cancer Hospital, Changsha

510515

Nanfang Hospital of Southern Medical University, Guangzhou

All Listed Sponsors
collaborator

Fujian Cancer Hospital

OTHER_GOV

collaborator

The Second Affiliated Hospital of Fujian Medical University

OTHER

collaborator

The Nanping First Affiliated Hospital of Fujian Medical University

UNKNOWN

collaborator

Quanzhou First Hospital

OTHER

collaborator

Fujian Medical University Union Hospital

OTHER

collaborator

Zhangzhou Affiliated Hospital of Fujian Medical University

OTHER

collaborator

Hunan Cancer Hospital

OTHER

collaborator

Jiangxi Provincial Cancer Hospital

OTHER

collaborator

900 Hospital of Joint Logistics Support Force of PLA

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

The First Affiliated Hospital of Xiamen University

OTHER

collaborator

Zhongshan Hospital Xiamen University

OTHER

lead

Jinsheng Hong

OTHER

NCT04823468 - Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma | Biotech Hunter | Biotech Hunter