PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2

NARecruitingINTERVENTIONAL
Enrollment

1,302

Participants

Timeline

Start Date

June 24, 2021

Primary Completion Date

January 1, 2026

Study Completion Date

February 1, 2026

Conditions
Infection
Interventions
PROCEDURE

Transperineal MRI-guided prostate biopsy

Transperineal prostate biopsy will be performed under local anesthesia in the office. This approach avoids transrectal needle tracking.

PROCEDURE

Transrectal MRI-guided prostate biopsy

Transrectal prostate biopsy is currently the most popular approach to evaluate a positive screening test for prostate cancer.

DRUG

Antibiotic (prophylaxis)

"For men undergoing transrectal biopsy, antibiotic prophylaxis will be administered in accordance with guidelines from the American Urological Association (AUA).~No antibiotic prophylaxis will be administered for men undergoing transperineal biopsy."

Trial Locations (16)

10065

RECRUITING

Memorial Sloan Kettering Cancer Center, New York

11217

COMPLETED

NewYork-Presbyterian Brooklyn Methodist Hospital, Brooklyn

11355

RECRUITING

NewYork-Presbyterian Queens, Flushing

19027

RECRUITING

Einstein Healthcare Network, Elkins Park

19104

RECRUITING

University of Pennsylvania, Philadelphia

19111

RECRUITING

Fox Chase Cancer Center, Philadelphia

20007

RECRUITING

Georgetown University, Washington D.C.

21287

RECRUITING

Johns Hopkins University, Baltimore

27599

NOT_YET_RECRUITING

University of North Carolina, Chapel Hill

44106

RECRUITING

University Hospitals Cleveland Medical Center, Cleveland

48109

RECRUITING

University of Michigan, Ann Arbor

60611

RECRUITING

Northwestern University, Chicago

90033

NOT_YET_RECRUITING

University of Southern California, Los Angeles

06030

RECRUITING

University of Connecticut, Farmington

02115

RECRUITING

Brigham and Women's Hospital, Boston

02215

NOT_YET_RECRUITING

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

Weill Medical College of Cornell University

OTHER