Remote Ischaemic Conditioning in STEMI Patients in AFRICA

NARecruitingINTERVENTIONAL
Enrollment

1,400

Participants

Timeline

Start Date

January 12, 2022

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
STEMIRemote Ischaemic ConditioningMyocardial Reperfusion Injury
Interventions
DEVICE

Remote Ischaemic Conditioning (RIC)

The RIC protocol will comprise inflation of the automated RIC device to 20 mmHg above systolic blood pressure for 5 minutes and deflation for a further 5 minutes, a cycle which will be completed four times in total. The RIC protocol will be repeated daily for the next 2 days.

DEVICE

Sham-control

The sham protocol will comprise low-pressure inflation to 20 mmHg for 5 minutes and deflation for a further 5 minutes, a cycle which will be completed four times in total by a visually identical pneumatic cuff used in the active arm. The sham control protocol will be repeated daily for the next 2 days.

Trial Locations (20)

2193

RECRUITING

Charlotte Maxeke Hospital, Johannesburg

2574

RECRUITING

Tshepong Hospital, Klerksdorp

4026

RECRUITING

Wentworth Hospital, Durban

6530

RECRUITING

George Hospital, George

7785

RECRUITING

Mitchell's Plain District Hospital, Cape Town

8000

RECRUITING

Groote Schuur Hospital, Cape Town

RECRUITING

Victoria Hospital, Cape Town

Unknown

RECRUITING

Coast General Teaching Hospital, Mombasa

RECRUITING

Mombasa Hospital, Mombasa

RECRUITING

Kenyatta National Hospital, Nairobi

RECRUITING

Nairobi West hospital, Nairobi

RECRUITING

Hospital Central de Mpauto, Maputo

RECRUITING

Hopital Principal de Dakar, Dakar

RECRUITING

Al Saha Specialised Hospital, Khartoum

RECRUITING

Al Shaab Teaching Hospital, Khartoum

RECRUITING

Sudan Heart Centre, Khartoum

RECRUITING

The Royal Care International Hospital, Khartoum

RECRUITING

Aliaa Specialist Hospital, Omdurman

RECRUITING

Medani Heart Centre, Wad Medani

RECRUITING

Uganda Heart Institute, Kampala

All Listed Sponsors
collaborator

Groote Schuur Hospital, South Africa

UNKNOWN

collaborator

Uganda Heart Institute

OTHER

collaborator

Mombasa Hospital, Kenya

UNKNOWN

collaborator

Coast General Teaching Hospital, Kenya

UNKNOWN

collaborator

Kenyatta National Hospital

OTHER_GOV

collaborator

Al Shaab Teaching Hospital, Sudan

UNKNOWN

collaborator

Sudan Heart Centre, Sudan

UNKNOWN

collaborator

Aliaa Specialist Hospital, Sudan

UNKNOWN

collaborator

Medani Heart Centre, Sudan

UNKNOWN

collaborator

Al Saha Specialised Hospital, Sudan

UNKNOWN

collaborator

Omdurman Hospital, Sudan

UNKNOWN

collaborator

Victoria Hospital, South Africa

UNKNOWN

collaborator

George Hospital, South Africa

UNKNOWN

collaborator

Charlotte Maxeke Hospital, South Africa

UNKNOWN

collaborator

Tshepong Hospital, South Africa

UNKNOWN

collaborator

Wentworth Hospital, South Africa

UNKNOWN

collaborator

Grey's Hospital

OTHER

collaborator

Universitas Academic Hospital, South Africa

UNKNOWN

collaborator

University College, London

OTHER

collaborator

Royal Care international Hospital, Sudan

UNKNOWN

collaborator

Nairobi West Hospital, Kenya

UNKNOWN

lead

University of Cape Town

OTHER