Transspinal Stimulation Plus Locomotor Training for SCI

NACompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

August 1, 2021

Primary Completion Date

December 1, 2024

Study Completion Date

December 31, 2024

Conditions
Spinal Cord InjuriesParaplegia, SpinalTetraplegia/TetraparesisParaplegia, Spastic
Interventions
COMBINATION_PRODUCT

Standing transspinal stimulation followed by robotic gait training

Fifteen people with spinal cord injury will receive 40 daily sessions of 30 minutes of non-invasive high frequency (e.g. 30 Hz) transcutaneous transspinal stimulation during standing followed by 30 minutes of assisted stepping robotic gait training. Before and after training standardized clinical and neurophysiological tests will be used to assess recovery of sensorimotor function.

COMBINATION_PRODUCT

Lying transspinal stimulation followed by robotic gait training

Fifteen people with spinal cord injury will receive 40 daily sessions of 30 minutes of non-invasive high frequency (e.g. 30 Hz) transcutaneous transspinal stimulation while lying supine on a therapy table followed by 30 minutes of assisted stepping robotic gait training. Before and after training standardized clinical and neurophysiological tests will be used to assess recovery of sensorimotor function.

OTHER

Standing sham transspinal stimulation followed by robotic gait training

Fifteen people with spinal cord injury will receive 40 daily sessions of 30 minutes of sham transspinal stimulation during standing at an intensity where sensation is absent followed by 30 minutes of robotic gait training. Before and after training standardized clinical and neurophysiological tests will be used to assess recovery of sensorimotor function.

Trial Locations (2)

10314

Department of Physical Therapy, Motor Control and NeuroRecovery Laboratory, Staten Island

10468

Veterans Affairs Medical Center, The Bronx

All Listed Sponsors
collaborator

Bronx Veterans Medical Research Foundation, Inc

OTHER

collaborator

Icahn School of Medicine at Mount Sinai

OTHER

lead

City University of New York

OTHER

NCT04807764 - Transspinal Stimulation Plus Locomotor Training for SCI | Biotech Hunter | Biotech Hunter