Changes in the Microvascular Reactivity on Leg During Spinal Anesthesia

CompletedOBSERVATIONAL
Enrollment

51

Participants

Timeline

Start Date

December 29, 2016

Primary Completion Date

December 31, 2017

Study Completion Date

December 31, 2017

Conditions
Spinal Anesthesia
Interventions
DIAGNOSTIC_TEST

Vascular occlusion test

The VOT procedure was conducted twice in each patient, before and 15 min after intrathecal injection. An NIRS sensor (INVOSTM 5100C Cerebral/Somatic Oximeter; Medtronic, Minneapolis, MN, USA) was attached to the patient's gastrocnemius muscle. A tourniquet (A.T.S ® 3000 Automatic Tourniquet System; Zimmer Inc., Warsaw, IL, USA) was applied to the thigh and inflated to a pressure value 50 mmHg over the patient's baseline systolic blood pressure in the leg and maintained for 5 min. After a 5-min ischemic period, the tourniquet was rapidly deflated to 0 mmHg. The StO2 data was continuously recorded during the VOT procedure. After confirmation of spinal anesthesia using cold sensitivity, the VOT procedure was repeated in the same manner as mentioned above. The occlusion slope and recovery slope were calculated based on the measured StO2 data.

Trial Locations (1)

49241

Pusan National University Hopsital, Busan

All Listed Sponsors
lead

Pusan National University Hospital

OTHER

NCT04806997 - Changes in the Microvascular Reactivity on Leg During Spinal Anesthesia | Biotech Hunter | Biotech Hunter