Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

NARecruitingINTERVENTIONAL
Enrollment

106

Participants

Timeline

Start Date

June 15, 2021

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Autism Spectrum Disorder
Interventions
DEVICE

Continuous Theta Burst Stimulation

Continuous theta burst stimulation (cTBS) will be applied using a MagPro X100 (MagVenture, Inc. Alpharetta, GA). The cTBS protocol consists of bursts of three pulses of 50 Hz stimulation repeated at 200 ms intervals (5 times per second) for 40 seconds (for a total of 600 pulses). Stimulation will be applied at an intensity of 80% of active motor threshold (AMT). Brainsight (Rogue Research) frameless neuronavigation system will be used to target the specific structural MRI-defined region of stimulation.

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Mental Health (NIMH)

NIH