Preoperative High-dose Dexamethasone and Emergency Laparotomy

PHASE4CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

October 9, 2022

Study Completion Date

December 9, 2022

Conditions
Intestinal Obstruction and IleusPerforated ViscusSepsisPathophysiologyInflammatory Response
Interventions
DRUG

Dexamethasone 1 mg/kg

Dexamethasone 1 mg/kg administered as a single preoperative i.v. infusion over 10-15 min prior to general anaesthesia

DRUG

Physiologic saline

100 mL Physiologic saline administered as a single preoperative i.v., infusion over 10-15 min prior to general anaesthesia

Trial Locations (1)

2650

Mirjana Cihoric, Hvidovre

All Listed Sponsors
lead

Mirjana Cihoric

OTHER

NCT04791566 - Preoperative High-dose Dexamethasone and Emergency Laparotomy | Biotech Hunter | Biotech Hunter