Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Postoperative Analgesia

PHASE4CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

April 9, 2021

Primary Completion Date

September 7, 2022

Study Completion Date

October 7, 2022

Conditions
Scoliosis CorrectionPostoperative AnalgesiaS-ketamineDexmedetomidineSufentanil
Interventions
DRUG

S-ketamine

S-ketamine 50 mg is included in the mixture for patient-controlled analgesia.

DRUG

Dexmedetomidine

Dexmedetomidine 200 microgram is included in the mixture for patient-controlled analgesia.

DRUG

Sufentanil

Sufentanil 4 microgram/kg (maximum 250 microgram) is included in the mixture for patient-controlled analgesia.

Trial Locations (1)

100034

Peking University First Hospital, Beijing

All Listed Sponsors
lead

Peking University First Hospital

OTHER