NCT04789499 - Smell in Covid-19 and Efficacy of Nasal Theophylline | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 15, 2021

Primary Completion Date

December 30, 2021

Study Completion Date

December 30, 2021

Conditions

Covid19AnosmiaOlfactory DisorderCovid-19 PandemicSARS-CoV-2 InfectionHyposmiaAgeusiaHypogeusia

Interventions

DRUG

Theophylline Powder

Twice daily nasal irrigation with 400 mg theophylline capsules and USP Grade Sodium Chloride \& Sodium Bicarbonate Mixture (pH balanced, Isotonic \& Preservative \& Iodine Free) commercially prepared packets dissolved in 240 ml of distilled water.

DRUG

Placebo Comparator

Twice daily nasal irrigation with 500 mg lactose powder capsules and USP Grade Sodium Chloride \& Sodium Bicarbonate Mixture (pH balanced, Isotonic \& Preservative \& Iodine Free) commercially prepared packets dissolved in 240 ml of distilled water.

Trial Locations (1)

63110

Washington University School of Medicine in Saint Louis, St Louis

All Listed Sponsors

lead

Washington University School of Medicine

OTHER