182
Participants
Start Date
March 24, 2021
Primary Completion Date
October 22, 2021
Study Completion Date
May 31, 2022
Conventional CLOSE-guided pulmonary vein isolation
Point-by-point RF delivery will be performed aiming for a contiguous circle enclosing the veins. RF will be delivered in a temperature and flow-controlled mode (QMODE, target temperature 45°C, low flow temperature 40°C, cut-off temperature 50°C) with a power of 35W(posterior)/50W(anterior) (irrigation flow at 4-15ml/min). RF will be delivered until an ablation index (AI) of ≥400 at the posterior wall/roof/south pole and ≥550 at the anterior wall.
High power short duration pulmonary vein isolation
Point-by-point RF delivery will be performed aiming for a contiguous circle enclosing the veins. RF will be delivered in temperature-controlled mode (QMode+, target temperature 55°C, cut-off temperature 65°C) with a power of 90W (irrigation flow at 2-8ml/min). RF will be delivered for 4 sec at both the posterior and anterior wall.
AZ Sint-Jan Brugge-Oostende AV, Bruges
Medical University Hospital Graz, Graz
UMC Leiden, Leiden
Luzerner Kantonsspital, Lucerne
AZ Sint-Jan AV
OTHER