Local Remodelling of Bone Fracture Healing

NACompletedINTERVENTIONAL
Enrollment

106

Participants

Timeline

Start Date

December 10, 2015

Primary Completion Date

January 17, 2019

Study Completion Date

December 19, 2019

Conditions
Fracture HealingDistal Radius Fracture
Interventions
DIAGNOSTIC_TEST

HR-pQCT (high resolution computertomograph)

In addition to determining the bone density, a quantitative bone structure analysis with measurement of the number of thickness and distribution of the trabeculae can also be carried out. In addition, the finite element analysis (FEA) allows strength models of the examined bone to be created from the data of the hr-pqCTs. In this way, the osseous consolidation of the fracture can not only be observed, but also tested for resilience with the help of mathematical models.

DIAGNOSTIC_TEST

Blood withdrawal

Bone remodeling blood marker: S-CTX (Crosslaps), S-TRA5b ( tartrate-resistant acid phosphatase), S-PINP (Procollagen type 1 amino-terminal propeptide), BALP, Calcium, parathyroid hormone, 25-OH-Vitamin D3 (HPLC)

All Listed Sponsors
collaborator

ETH Zurich

OTHER

collaborator

University Hospital Ulm

OTHER

lead

Medical University Innsbruck

OTHER

NCT04783337 - Local Remodelling of Bone Fracture Healing | Biotech Hunter | Biotech Hunter