NCT04780945 - Functional Analysis of BRCAness | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 21, 2019

Primary Completion Date

December 21, 2022

Study Completion Date

June 21, 2023

Conditions

Ovarian Neoplasm EpithelialHomologous Recombination DeficiencyBRCA1 MutationBRCA2 Mutation

Interventions

DIAGNOSTIC_TEST

Functional RAD51 assay

ex vivo functional assay (RAD51 assay also known as Repair Capacity (RECAP) assay ) to test homologous recombination deficiencie (HRD) in viable tumor tissue

DRUG

Olaparib Oral Product

300 mg bid

Trial Locations (3)

Unknown

RECRUITING

University Medical Center Groningen, Groningen

NOT_YET_RECRUITING

Erasmus Medical Center, Rotterdam

2300RC

RECRUITING

Leiden University Medical Center, Leiden