Dietary Supplements for COVID-19

PHASE3TerminatedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 12, 2021

Primary Completion Date

May 3, 2022

Study Completion Date

July 7, 2022

Conditions
Covid19
Interventions
DRUG

Vitamin D3 50,000 IU

This is a loading dose of Vitamin D. Vitamin D (cholecalciferol \[vitamin D3\]) is a fat-soluble vitamin that is synthesized following ultraviolet radiation to the skin, naturally occurs in a few dietary sources and is available as a dietary supplement.

DIETARY_SUPPLEMENT

Vitamin C/Zinc

This is a combination of Vitamin C and Zinc. Vitamin C (ascorbic acid, ascorbate) is a water-soluble vitamin that naturally occurs in many foods and is sold as a dietary supplement. It is required for the functioning of several enzymes and is important for the immune system. Zinc is one of the most abundant essential trace elements in the human body and is required for the function of several hundred enzymes and transcription factors.

DIETARY_SUPPLEMENT

Vitamin K2/D

This is a combination of Vitamin K2 (menaquinone-7) and vitamin D. Vitamin K (menaquinone-7 \[vitamin K2\]) is a fat-soluble vitamin found in foods and sold as a dietary supplement. Vitamin K plays a large role in synthesizing coagulation factors in the blood, and vitamin K deficiency has been associated with uncontrolled bleeding. Vitamin K1 (phylloquinone) is an alternate form of vitamin K found in foods and supplements; however, vitamin K2 has a better absorption profile50 and additionally plays a role in bone metabolism controlling the binding of calcium, especially in older adults, where it attenuates the rate of bone loss

OTHER

Microcrystalline Cellulose Capsule

Placebo equivalent of Vitamin C/Zinc and Vitamin D3.

OTHER

Medium Chain Triglyceride Oil

Placebo equivalent of Vitamin K2/D

Trial Locations (1)

K2P0M7

The Centre for Health Innovation, Ottawa

Sponsors
All Listed Sponsors
collaborator

Ottawa Hospital Research Institute

OTHER

collaborator

Vitazan Professional

OTHER

collaborator

New Roots Herbal

INDUSTRY

lead

The Canadian College of Naturopathic Medicine

OTHER