NCT04779554View on ClinicalTrials.gov

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

PHASE2RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 4, 2021

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
Peritoneal Carcinomatosis
Interventions
DRUG

Mitomycin C, flat dose 40 mg

Mitomycin C will be delivered as heated intraperitoneal chemotherapy (HIPEC) in two flat doses. Dose 1 will be 30mg at minute 0 and dose 2 will be 10 mg at minute 60.

DRUG

Mitomycin C, weight-based dose 12.5 mg/m2

Mitomycin C will be delivered as heated intraperitoneal chemotherapy (HIPEC) in two weight-based doses of 9 mg/m2 at minute 0 and 3 mg/m2 at minute 60.

Trial Locations (2)

40536

RECRUITING

University of Kentucky, Lexington

05401

RECRUITING

University of Vermont Medical Center, Burlington

All Listed Sponsors
lead

Prakash Pandalai

OTHER