Open-Label Extension Study of Trofinetide for Rett Syndrome

PHASE3TerminatedINTERVENTIONAL
Enrollment

77

Participants

Timeline

Start Date

November 8, 2020

Primary Completion Date

June 30, 2023

Study Completion Date

June 30, 2023

Conditions
Rett Syndrome
Interventions
DRUG

trofinetide

Study drug is administered twice a day for up to approximately 32 months. Doses may be taken orally or administered by gastrostomy (G) tube. The subject's assigned dose for this study will be the final dose from the antecedent study (ACP-2566-004).

Trial Locations (21)

10467

Montefiore Medical Center, The Bronx

19104

Children's Hospital of Philadelphia, Philadelphia

21205

Kennedy Krieger Institute, John Hopkins School of Medicine, Baltimore

27599

The University of North Carolina at Chapel Hill, Chapel Hill

29646

Greenwood Genetic Center, Greenwood

30322

Emory Genetics Clinical Trial Center, Atlanta

33612

University of South Florida, Tampa

35233

University of Alabama at Birmingham, Birmingham

37232

Vanderbilt University Medical Center, Nashville

44195

Cleveland Clinic, Cleveland

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

55101

Gillette Children's Specialty Healthcare, Saint Paul

60612

Rush University Medical Center, Chicago

63110

Washington University School of Medicine, St Louis

77030

Texas Children's Hospital, Houston

80045

Children's Hospital Colorado Aurora, Aurora

85012

Translational Genomics Research Institute (TGen), Phoenix

92037

University of California, San Diego, La Jolla

95817

UC Davis MIND Institute, Sacramento

98105

Seattle Children's Hospital, Seattle

02115

Boston Children's Hospital Harvard Medical School, Boston

Sponsors
All Listed Sponsors
lead

ACADIA Pharmaceuticals Inc.

INDUSTRY