200
Participants
Start Date
April 22, 2021
Primary Completion Date
October 6, 2023
Study Completion Date
December 1, 2023
Cefazolin
Cefazolin is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. Cefazolin (2 g will be administrated intravenously (IV) every 8 hours for 4-6 weeks)
Dalbavancin
A second-generation lipoglycopeptide antibiotic synthesized from a fermentation product of Nonomuraea species
Daptomycin
Daptomycin (USA) or Cubicin (Spain) is a cyclic lipopeptide antibiotic that inhibits gram-positive bacteria. Daptomycin (6-10 mg/kg will be administrated intravenously (IV) daily for 4-6 weeks
Nafcillin
Nafcillin is a semi-synthetic antibiotic related to penicillin. Nafcillin (2 g will be administrated intravenously (IV) every 4 hours for 4-6 weeks)
Oxacillin
Oxacillin is an antibiotic used in resistant staphylococci infections. Oxacillin (2 g will be administrated intravenously (IV) every 4 hours for 4-6 weeks
Vancomycin
Vancomycin is a glycopeptide antibiotic product of the organism Amycolatopsis orientalis. Vancomycin (dose per local standard of care × 4-6 weeks)
SUNY Upstate Medical University - Infectious Disease Division, Syracuse
University of Pittsburgh - Medicine - Infectious Diseases, Pittsburgh
University of South Florida Health - Internal Medicine, Tampa
Carilion Roanoke Memorial Hospital, Roanoke
Wake Forest Baptist Medical Center, Winston-Salem
Duke University Hospital - Infectious Diseases, Durham
Atrium Health ID Consultants & Infusion Care Specialists, Charlotte
Prisma Health - Greenville Health System - Infectious Disease, Greenville
University of Florida Health - Shands Hospital - Division of Infectious Diseases and Global Medicine, Gainesville
University of Alabama Hospital - Infectious Diseases, Birmingham
Rush University Medical Center, Chicago
Ochsner Health - Ochsner Medical Center - Department of Infectious Diseases, New Orleans
Torrance Memorial Medical Center, Torrance
University of California Davis Medical Center - Internal Medicine - Infectious Disease, Sacramento
Harbor UCLA Medical Center - Medicine - Infectious Diseases, Torrance
Henry Ford Health System - Henry Ford Hospital, Detroit
Corewell Health - Infectious Disease, Royal Oak
University of Nebraska Medical Center - Infectious Diseases, Omaha
South Jersey Infectious Disease, Somers Point
New York Presbyterian Hospital - Weill Cornell Medical Center - Infectious Diseases, New York
East Carolina University - Infectious Diseases and Tropical/Travel Medicine Clinic, Greenville
Oregon Health and Science University - Adult Infectious Diseases Clinic, Portland
The University of Texas - MD Anderson Cancer Center - Infectious Diseases, Houston
McGill University Health Centre, Montreal
National Institute of Allergy and Infectious Diseases (NIAID)
NIH