High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

December 30, 2020

Primary Completion Date

June 30, 2025

Study Completion Date

August 28, 2025

Conditions
Congenital Diaphragmatic Hernia
Interventions
DEVICE

High Frequency Jet Ventilator

HFJV provides short bursts of gas into the respiratory circuit at a rate of 240 to 600/min (4 to 11 Hz) and expiration is passive. It is used in conjunction with a conventional ventilator which provides positive end expiratory pressure (PEEP) and can also provide occasional sigh breaths.

DEVICE

High Frequency Oscillatory Ventilator

HFOV uses a piston diaphragm to generate alternating positive and negative pressure changes to give breaths of 300 to 900/min (5-15 Hz) given over a set mean airway pressure. Both inhalation and exhalation are active.

Trial Locations (2)

84113

RECRUITING

Primary Children's Hospital, Salt Lake City

84132

RECRUITING

University Hospital, Salt Lake City

All Listed Sponsors
lead

University of Utah

OTHER

NCT04774848 - High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia | Biotech Hunter | Biotech Hunter