Effectiveness of High-frequency rTMS in Reducing Alcohol Consumption in Non-abstinent Patients With an Alcohol Use Disorder

NARecruitingINTERVENTIONAL
Enrollment

144

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
AlcoholismrTMS Stimulation
Interventions
DEVICE

Active rTMS

"Two rTMS stimulation sessions spaced 15 minutes apart are delivered daily for 5 consecutive days.~A total of 10 sessions. Stimulation parameters: 10 Hz, 1000 pulses per session, 110% of SM, cortical target: right DLPFC"

DEVICE

Placebo rTMS

"Two rTMS stimulation sessions spaced 15 minutes apart are delivered daily for 5 consecutive days.~A total of 10 sessions. Stimulation parameters: delivering a non-significant current at the beginning and end of the stimulation, simulating active stimulation."

OTHER

Questionnaires

questionnaires for craving assessment: EVA, OCDS, CGI and ADS and signs of physical withdrawal by CIWA

DEVICE

Breathalyzer

estimation of blood alcohol level

Trial Locations (1)

21000

RECRUITING

Chu Dijon Bourogne, Dijon

All Listed Sponsors
lead

Centre Hospitalier Universitaire Dijon

OTHER